Mental/Emotional System – Cannabis and Cannabinoid Research

Mental/Emotional System Research Dashboard

412

Primary Studies

171

Related Studies

583

Total Studies

Clinical Studies

47

Double-blind human trials

37

Clinical human trials

Pre-Clinical Studies

190

Meta-analyses/Reviews

133

Animal studies

5

Laboratory studies

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CannaKeys has 583 studies associated with Mental/Emotional System.

Here is a small sampling of Mental/Emotional System studies by title:


Components of the Mental/Emotional System Research Dashboard

  • Medical conditions associated with Mental/Emotional System
  • Synopsis of cannabis research for Mental/Emotional System
  • Chemotype guidance for Mental/Emotional System
  • Individual study details for Mental/Emotional System

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Overview - Mental/Emotional System

Description of Mental/Emotional System

Mental, Behavioral, Neurodevelopmental Disorders (MBND) affect the equilibrium of our mental-emotional or psychological system in addition to producing associated physiological and behavioral changes, which is defined by the manifestations of specific signs and symptoms on one hand but also by a sense or a lack of well-being and resilience in the face of common stressors on the other. Stress or distress (especially when chronic or acute) in the patients state of mind, in their personal or family spheres, at work and in the context of interaction with other elements of society are major and measurable indicators that can affects all other organ system. As such, these MBND are a significant and detrimental factor contributing to other chronic conditions and to increasing the vulnerability to developing additional co-morbidities.

Mental/Emotional System and ECS-Based Interactions

Cannabis works for so many different patient populations is because it affects the body and the mind in such a way as to support and fortify the body’s capacity for self-healing. Fact is, the right type of cannabis, at the proper dose, matched to each patient’s individual needs will produce two things: one, it will induce a deep sense of relaxation and two, it will produce multiple system homeostasis at a cellular level.

Mental/Emotional System Medical Specialists

Psychologist, Psychiatrist, Psychosomaticist, Psychopathologist

Also Known As:

Mental, Behavioral, Neurodevelopmental System

Drug Interactions

THC Interaction with Pharmaceutical Drugs

  • THC can enhance the effects of drugs that cause sedation and depress the central nervous system, such as benzodiazepines, barbiturates, and alcohol, for example. 
  • THC is metabolized by and an inhibitor of a number of enzymatic liver pathways referred to as cytochrome P450. There are more than 50 enzymes belonging to this enzyme family, a number of which are responsible for the breakdown of common drugs such as antidepressants (e.g. amitriptyline, doxepine, fluvoxamine), antipsychotics (haloperidol, clozapine, stelazine), or beta-blockers (propranolol, theophylline, warfarin).  Thus patients taking these classes of medication may find that THC increases the concentration and effects of these drugs as well as the duration of their effects.
  • Clinical observation suggests no likely interactions with other pharmaceuticals at a total daily dose of up to 20mg THC.

CBD Interaction with Pharmaceutical Drugs

  • CBD may alter action on metabolic enzymes (certain drug-transport mechanisms), and as such may alter interactions with other drugs, some of which may produce therapeutic or adverse effects. For instance, CBD interacts with the enzyme cytochrome P450 3A4 and cytochrome P450 2C19, increasing the bioavailability of anti-epileptic drugs such as clobazam (a benzodiazepine). This makes it possible to achieve the same results at significantly lower dosages, reducing treatment costs and risks of adverse effects. 
  • Groups of drugs affected include: anti-epileptic drugs, psychiatric drugs, and drugs affecting metabolic enzymes, for example.
  • Clinical observations suggest no likely interactions with other pharmaceuticals at a total daily dose of up to 100mg CBD

Dosing Considerations

THC Dosage Considerations

  • THC micro dose:  0.1 mg to 0.4 mg (0.001mg/kg to 0.005mg/kg)
  • THC low dose:  0.5 mg to 5 mg (0.006mg/kg to 0.06mg/kg)
  • THC medium dose:  6 mg to 20 mg (0.08mg/kg to 0.27mg/kg)
  • THC high dose:  21 mg to 50+ mg (0.28mg/kg to 0.67mg/kg)
Formula for converting a set dose into mg/kg considerations: mg ÷ kg = mg/kg
(sample conversion calculated on a person weighing 75kg)

CBD Dosage Considerations

  • CBD low dose:  0.4 mg to 19 mg (0.005mg/kg to 0.25mg/kg)
  • CBD medium dose: 20 mg to 99 mg (0.26mg/kg to 1.32mg/kg)
  • CBD high dose:  100 mg to 800+ mg (1.33mg/kg to 10.7mg/kg)
  • (upper limits tested ~1,500mg)
Formula for converting a set dose into mg/kg considerations: mg ÷ kg = mg/kg
(sample conversion calculated on a person weighing 75kg)

Disclaimers: Information on this site is provided for informational purposes only and is not meant to substitute for the advice provided by your own physician or other medical professional. You should not use the information contained herein for diagnosing a health problem or disease. If using a product, you should read carefully all product packaging. If you have or suspect that you have a medical problem, promptly contact your health care provider.

Information on this site is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your physician, nutritionally oriented health care practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications.