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Cannabidiol (CBD) Cannabinoid Research

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Overview - Cannabidiol (CBD)

Description of Cannabidiol (CBD)

Cannabidiol (CBD) was discovered in 1940. By 2021, there were 14 proposed members in the CBD family (i.e., CBD, CBDA-C5, CBDV, CBDM-C5, CBD-C1, CBD-C4, CBDVA-C3, CMPD1, CMPD5, CMPD6, CMPD16, CMPD18, CBDH, CBDB). CBD is a significant cannabinoid that occurs naturally in cannabis in amounts large enough to produce various and substantial changes in the human body, mind, and emotions.


Unlike its psychoactive sister, compound THC, CBD does not induce changes in cognition but is quite capable of generating a gentle uplift in affect (or mood), which is why the growing body of clinical trials indicates its therapeutic potential in several mood disorders or psychiatric conditions such as:



  • Alcohol Dependence, Withdrawal, and Intoxication

  • Anorexia Nervosa

  • Anxiety and Panic Disorders

  • Attention Deficit and Hyperkinetic Disorders

  • Autism and Pervasive Developmental Disorders

  • Behavioral Disorders

  • Benzodiazepine Use Disorder

  • Bipolar Affective Disorder

  • Cannabis Adverse Effects

  • Cannabis Use Disorder

  • Cocaine Dependence

  • Depression

  • Domestic Abuse

  • Grief, Bereavement, and Adjustment Disorders

  • Intermittent Explosive Disorder

  • Loss of Appetite

  • Nicotine Dependence and Withdrawal

  • Obsessive Compulsive Disorder

  • Opioid Dependency and Overdose

  • Post-Traumatic Stress Disorder

  • Psychosis

  • Schizophrenia

  • Stress and Life Management Difficulty

  • Suicide Attempt

  • Stimulant Dependence and Psychosis

  • Stuttering


Dosing Range: A systematic review of clinical trials (2019) reported effective oral CBD doses between 1 and 50 mg/kg/d (average 15 mg/kg/d) in treating various conditions.

Other Names:

Cannabidiol

(-)-Cannabidiol, (-)-trans-Cannabidiol, Epidiolex, Oravexx, and other supplier-based synonyms.


IUPAC Name: 2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylbenzene-1,3-diol


Molecular Formula: C21H30O2


Source–PubChem

Cannabidiol (CBD) Properties and Effects

Only Members can view Properties and Effects information. See DEMO page.

Cannabidiol (CBD) Receptor Binding

Only Members can view Receptor Binding information. See DEMO page.

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Disclaimer
Information on this site is provided for informational purposes only and is not meant to substitute for the advice provided by your own licensed physician or other medical professional. You should not use the information contained herein for diagnosing or treating a health problem or disease. If using a product, you should read carefully all product packaging. If you have or suspect that you have a medical problem, promptly contact your health care provider.

Information on this site is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your physician, nutritionally oriented health care practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications.