To see a full dashboard with study details and filtering, go to our DEMO page.
As a subscriber, you will be able to access dashboard insights including chemotype overviews and dosing summaries for medical conditions and organ system and receptor breakdowns for cannabinoid and terpene searches. Study lists present important guidance including dosing and chemotype information with the ability to drill down to the published material. And all outputs are fully filterable, to help find just the information you need. Stay up-to-date with the science of cannabis and the endocannabinoid system with CannaKeys.
Here is a small sampling of Cognitive Dysfunction studies by title:
Ready to become a subscriber? Go to our PRICING page.
To see a full dashboard with study details and filtering, go to our DEMO page.
As a subscriber, you will be able to access dashboard insights including chemotype overviews and dosing summaries for medical conditions and organ system and receptor breakdowns for cannabinoid and terpene searches. Study lists present important guidance including dosing and chemotype information with the ability to drill down to the published material. And all outputs are fully filterable, to help find just the information you need. Stay up-to-date with the science of cannabis and the endocannabinoid system with CannaKeys.
Here is a small sampling of Cognitive Dysfunction studies by title:
Ready to become a subscriber? Go to our PRICING page.
Cognitive functions encompass essential mental processes, including perceiving, discerning, imagining, and remembering. Cognitive decline is the progressive reduction of these abilities, impacting memory, attention, reasoning, and decision-making. While mild cognitive changes are a natural part of aging, the distinction between optimal and suboptimal aging is crucial.
Optimal aging involves preserving robust cognitive function through healthy lifestyle choices, mental stimulation, and effective disease management. In contrast, suboptimal aging is characterized by accelerated cognitive decline driven by factors such as chronic inflammation, oxidative stress, poor lifestyle habits, and untreated health conditions like cardiovascular disease or diabetes.
Initially, cognitive decline may manifest as difficulties recalling recent events, multitasking, or processing information efficiently. Over time, these challenges can disrupt daily life, affecting problem-solving, communication, and emotional well-being. The central nervous system (CNS)—particularly the hippocampus, prefrontal cortex, and basal ganglia—is highly vulnerable to dysfunction. Neuroinflammation, oxidative stress, gut dysbiosis, mitochondrial health, and impaired neuroplasticity are key mechanisms underlying cognitive decline, especially in suboptimal aging.
Preventative strategies, including a balanced lifestyle and adequate medical care, are vital for mitigating cognitive decline. Emerging therapies, such as cannabinoid-based treatments and endocannabinoid system (ECS) modulators, show promise in reducing inflammation (i.e., “inflammaging”), promoting neuroprotection, neurogenesis, and restoring brain function, offering new hope for addressing cognitive health challenges.
If you are interested in the interaction potential of specific pharmaceuticals with THC, consider visiting these free drug interaction checkers: Drugs.com or DrugBank Online.
If you are interested in the interaction potential of specific pharmaceuticals with CBD, consider visiting these free drug interaction checkers: Drugs.com or DrugBank Online.
In general, when using cannabinoid-based therapeutics that contain both THC and CBD consider the ratio between them and weigh the relevant information displayed in the individual THC and CBD Drug Interaction windows accordingly.
If you are interested in the interaction potential of specific pharmaceuticals with both primary cannabinoids and THC/CBD, consider visiting these free drug interaction checkers: Drugs.com or DrugBank Online.
Concerns about Cannabis and Cancer-related Immunotherapies:
Some recent clinical observational studies have suggested that the co-administration of cannabinoid-based therapeutics and immunotherapy or immune checkpoint inhibitors in the treatment of certain types of cancer has been associated with worse overall survival rates (T. Taha et al., 2019; A. Biedny et al., 2020; G. Bar-Sela et al., 2020).
However, other studies have suggested that the co-commitment use of immune checkpoint inhibitors and cannabis-induced no such deleterious effects. More specifically, one trial was conducted on animals resulting in data suggesting that cannabis did not negatively affect the properties of immune checkpoint inhibitors (B. Waissengrin et al., 2023). The same authors compared the previous study results with findings from a cohort of 201 patients with metastatic non-small cell lung cancer who received treatment with monotherapy pembrolizumab as a first-line treatment and adjunct cannabis to treat mainly pain and loss of appetite. Their time to tumor progression was 6.1 versus 5.6 months, and overall survival differed between 54.9 versus 23.6 months in cannabis-naïve patients and cannabis-using patients, respectively. However, while numerically different, the authors write that these differences were not statistically significant, leading them to suggest that “These data provide reassurance regarding the absence of a deleterious effect of cannabis in this clinical setting.”
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Information on this site is provided for informational purposes only and is not meant to substitute for the advice provided by your own licensed physician or other medical professional. You
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medical problem, promptly contact your health care provider.
Information on this site is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your physician, nutritionally oriented health care practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications.