Tetrahydrocannabinolic Acid (THC-a) Research Dashboard
Loading research dashboard…
Page Quick Links
Loading filter…
Loading Primary Studies…
Loading Related Studies…
Overview - Tetrahydrocannabinolic Acid (THC-a)
Description of Tetrahydrocannabinolic Acid (THC-a)
Delta 9-Tetrahydrocannabinolic Acid (Delta-9-THCA) was discovered in 1969. It is the precursor to THC, the primary psychoactive phytocannabinoid. However, in its acid form, Delta-9-THCA is non-psychoactive.
Delta-9-THCA is found in fresh cannabis leaves, flowers, and related products. It becomes progressively decarboxylated and thus psychoactive during drying and when exposed to significant heat when heat-processed into oils or smoked.
Delta-9-THCA is better absorbed systemically than THC (M. Hannon et al., 2020).
Delta-9-THCA can penetrate the blood-brain barrier (BBB) and induce therapeutic effects on the central nervous system (CNS) (J. Kim et al., 2023)
Other Names:
Delta 9-Tetrahydrocannabinolic Acid9-carboxy-THC, THC-9-COOH, 9-Carboxy-delta(9)-thc plus numerous other supplier-based synonyms.
IUPAC Name: (6aR,10aR)-1-hydroxy-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydrobenzo[c]chromene-2-carboxylic acid
Molecular Formula: C22H30O4
Source–PubChem
Tetrahydrocannabinolic Acid (THC-a) Properties and Effects
Only Members can view Properties and Effects information. See DEMO page.
Tetrahydrocannabinolic Acid (THC-a) Receptor Binding
Only Members can view Receptor Binding information. See DEMO page.
Disclaimer
Information on this site is provided for informational purposes only and is not meant to substitute for the advice provided by your own licensed physician or other medical professional. You
should not use the information contained herein for diagnosing or treating a health problem or disease. If using a product, you should read carefully all product packaging. If you have or suspect that you have a
medical problem, promptly contact your health care provider.
Information on this site is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your physician, nutritionally oriented health care practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications.
