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Ocimene – Terpenes and Cannabinoid Research

Ocimene Research Dashboard

10

Primary Studies

12

Related Studies

22

Total Studies

Clinical Studies

0

Clinical Meta-analyses

0

Double-blind Clinical Trials

0

Clinical Trials

Pre-Clinical Studies

3

Meta-analyses/Reviews

3

Animal Studies

4

Laboratory Studies

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CannaKeys has 22 studies associated with Ocimene.

Here is a small sampling of Ocimene studies by title:

  • Healing of a Chronic Pressure Injury in a Patient Treated With Medical Cannabis for Pain and Sleep Improvement: A Case Report
  • Identification of Chemotypic Markers in Three Chemotype Categories of Cannabis Using Secondary Metabolites Profiled in Inflorescences, Leaves, Stem Bark, and Roots
  • A review on the traditional uses, phytochemistry, and pharmacological activities of clove basil (Ocimum gratissimum L.)
  • Analgesic Potential of Terpenes Derived from Cannabis sativa
  • The Anti-Inflammatory Properties of Terpenoids from Cannabis

Components of the Ocimene Research Dashboard

  • Top medical conditions associated with Ocimene
  • Proven effects in clinical trials for Ocimene
  • Receptors associated with Ocimene
  • Individual study details for Ocimene

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Overview - Ocimene

What is Ocimene?

Ocimene has a floral and perfume-like scent and is a flavoring agent and additive.


It is found in relatively low concentrations of cannabis but in higher concentrations in certain essential oils.


Ocimene is thought to possess anticonvulsant activity, antifungal activity, antibacterial activity, potential antihypertensive activity, and antitumor activity.


Is Ocimene safe?


Ocimene is a floral-smelling oil that, in its isolated form, can cause severe eye and skin irritation and can be fatal if aspirated.

Other Names

IUPAC Name: 3,7-dimethylocta-1,3,6-triene


Source–PubChem

Scent Description

Woody, vegetal, herbaceous

Natural Sources

Allspice, tarragon, basil, mint, parsley

Cannabis Strains High in Ocimene

Durban Poison, OG Kush, Dutch Treat, Sour Diesel, Strawberry Cough, Dream Queen, Chocolope

Ocimene Properties and Effects

Ocimene is associated with the following properties and effects:



  1. Anti-seizure (C. Okoli et al., 2010)

  2. Anxiolytic (C. Okoli et al., 2010)


Anti-inflammatory (via nitric oxide (NO) production inhibition, NO scavenging effect, and inhibited inducible NO synthase expression)


Anti-oxidant (via antiradical activity concerning OH and preventing the initiation of hydroxyl and superoxide radicals)


Anti-bacterial (via inhibiting growth of Proteus mirabilis, Staphylococcus aureus, Corynebacterium pseudotuberculosis, Klebsiella pneumonia, Pseudomonas aeruginosa, Enterobacter aerogenes, Salmonella enterica, and Streptococcus pyogenes when compared to standard antibiotics for positive control)


Anti-fungal (via inhibiting growth of dermatophytes and Cryptococcus neoformans)


Anti-tumor activity (via cytotoxicity in vitro on cancer cell lines of B16-F10 (mouse melanoma), HepG2 (human hepatocellular carcinoma), K562 (human chronic myelocytic leukemia) and HL-60 (human promyelocytic leukemia)


Possibly anticonvulsant and anxiolytic (via possible enhancement of GABAergic transmission)


Potentially anti-hypertensive and antidiabetic (via antioxidant activity, co-occurring phenolic content of ocimene-containing compounds like black pepper, and inhibiting α -amylase, α -glucosidase, and ACE enzyme activities in concentration-dependent manners)


Last reviewed by Dr. Abraham Benavides, M.D., 05-20-2022

Ocimene Receptor Binding

Endocannabinoid System (ECS) and Ocimene:



  1. CB1 (agonist) (N. Raz et al., 2023)


Endocannabinoidome (eCBome) and Ocimene:


N/A

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Information on this site is provided for informational purposes only and is not meant to substitute for the advice provided by your own licensed physician or other medical professional. You should not use the information contained herein for diagnosing or treating a health problem or disease. If using a product, you should read carefully all product packaging. If you have or suspect that you have a medical problem, promptly contact your health care provider.

Information on this site is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your physician, nutritionally oriented health care practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications.