ß-Caryophyllene – Terpenes and Cannabinoid Research

ß-Caryophyllene Research Dashboard


Primary Studies


Related Studies


Total Studies

Clinical Studies


Double-blind human trials


Clinical human trials

Pre-Clinical Studies




Animal studies


Laboratory studies

What am I missing as a non-subscriber?

To see a full dashboard with study details and filtering, go to our DEMO page.

As a subscriber, you will be able to access dashboard insights including chemotype overviews and dosing summaries for medical conditions and organ system and receptor breakdowns for cannabinoid and terpene searches. Study lists present important guidance including dosing and chemotype information with the ability to drill down to the published material. And all outputs are fully filterable, to help find just the information you need. Stay up-to-date with the science of cannabis and the endocannabinoid system with CannaKeys.

CannaKeys has 80 studies associated with ß-Caryophyllene.

Here is a small sampling of ß-Caryophyllene studies by title:

Components of the ß-Caryophyllene Research Dashboard

  • Top medical conditions associated with ß-Caryophyllene
  • Proven effects in clinical trials for ß-Caryophyllene
  • Receptors associated with ß-Caryophyllene
  • Individual study details for ß-Caryophyllene

Ready to become a subscriber? Go to our PRICING page.

Select New Terpene

Filter Terpene

Members can filter by the following criteria:

  • Study Type
  • Organ Systems
  • Cannabinoids & Endocannabinoids
  • Receptors
  • Ligands
  • Study Result
  • Year of Publication

Overview - ß-Caryophyllene


Beta-caryophyllene is a sesquiterpene that binds with CB2 receptors. Depending on concentration, its scent is described as spicy, peppery, with a strong warm, wooden aroma and an undertone of citrus.It is not uncommon for beta-caryophyllene to be the predominant terpenoid in cannabis.

Description of ß-Caryophyllene and Cautions

Beta-caryophyllene is a colorless and slightly oily liquid that has been approved by the FDA as a food additive for human consumption (FDA PART 172).

Scent Description

Black pepper, cloves, hops, cinnamon

Natural Sources

Black pepper, grains of Paradise, basil, Sri Lankan cinnamon, caraway

Summary of ß-Caryophyllene Effects

Immune-modulation, anti-inflammatory, neuroprotective (spasms, seizures, epilepsy, induces neuritogenesis); may protect from Alzheimer’s Disease and Vascular Dementia; may be beneficial in cases of colitis, IBS; anti-bacterial (tuberculosis, leprosy, Staphylococcus aureus, Pseudomonas aeruginosa); anti-fungal (Candida albicans, Aspergillus niger); may be protective against type-2 diabetes; may have anti-cancer properties (kidney, colon, pancreatic, melanoma, lymphoma); may produce a synergistic effect with certain chemotherapy agents (e.g. Paclitaxel), analgesic effects (in cases of inflammatory and neuropathic pain), antioxidant, may protect against binge drinking or chronic alcohol consumption-induced alcoholic steatohepatitis,nonalcoholic fatty liver disease, and steatosis (fatty liver diseases).

Cannabis Strains High in ß-Caryophyllene

Tickle Kush, SFV OG, Super Lemon Haze, Sherbert Breath

Disclaimers: Information on this site is provided for informational purposes only and is not meant to substitute for the advice provided by your own physician or other medical professional. You should not use the information contained herein for diagnosing a health problem or disease. If using a product, you should read carefully all product packaging. If you have or suspect that you have a medical problem, promptly contact your health care provider.

Information on this site is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your physician, nutritionally oriented health care practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications.