Monoacylglycerol Lipase (MAGL) Cannabinoid Research

Monoacylglycerol Lipase (MAGL) Research Dashboard

58

Primary Studies

113

Related Studies

171

Total Studies

Clinical Studies

0

Clinical Meta-analyses

0

Double-blind human trials

1

Clinical human trials

Pre-Clinical Studies

15

Meta-analyses/Reviews

30

Animal studies

12

Laboratory studies

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CannaKeys has 171 studies associated with Monoacylglycerol Lipase (MAGL).

Here is a small sampling of Monoacylglycerol Lipase (MAGL) studies by title:


Components of the Monoacylglycerol Lipase (MAGL) Research Dashboard

  • Top medical conditions associated with Monoacylglycerol Lipase (MAGL)
  • Proven effects in clinical trials for Monoacylglycerol Lipase (MAGL)
  • Receptors associated with Monoacylglycerol Lipase (MAGL)
  • Individual study details for Monoacylglycerol Lipase (MAGL)

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Overview - Monoacylglycerol Lipase (MAGL)

Description of Monoacylglycerol Lipase (MAGL)

Monoacylglycerol lipase (MAGL) is a naturally occurring key enzyme that breaks down the endocannabinoid 2-arachidonoylglycerol (2-AG) and as such is responsible for the inactivation 2-AG and the effects associated with it.


Most studies centered on MAGL explore what happens when the enzyme is inhibited from breaking down 2-AG and as such increase the bioavailability of 2-AG. The most extensively studied MGL inhibitor is JZL184.


Other more commonly appearing inhibitors that you may find in the scientific literature include: JZL-195, URB597, URB602, OMDM169.

Other Names:

Monoacylglycerol lipase

Monoacylglycerol lipase

Monoacylglycerol Lipase (MAGL) Properties and Effects

Inhibition of MAGL resulted in: 

Monoacylglycerol Lipase (MAGL) Receptor Binding

N/A

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Information on this site is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your physician, nutritionally oriented health care practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications.