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Here is a small sampling of Monoacylglycerol Lipase (MAGL) studies by title:
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Monoacylglycerol lipase (MAGL) is a naturally occurring key enzyme that breaks down the endocannabinoid 2-arachidonoylglycerol (2-AG) and as such is responsible for the inactivation 2-AG and the effects associated with it.
Most studies centered on MAGL explore what happens when the enzyme is inhibited from breaking down 2-AG and as such increase the bioavailability of 2-AG. The most extensively studied MGL inhibitor is JZL184.
Other more commonly appearing inhibitors that you may find in the scientific literature include: JZL-195, URB597, URB602, OMDM169.
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Only Members can view Receptor Binding information. See DEMO page.
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Information on this site is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your physician, nutritionally oriented health care practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications.