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HU-x Synthetic Cannabinoids Cannabinoid Research

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Overview - HU-x Synthetic Cannabinoids

Description of HU-x Synthetic Cannabinoids

The HU-x series are synthetic cannabinoids that carry the initials based on their place of discovery Hebrew University, Israel.


Here we focus on the (+) and (-) cannabinoid enantiomers of 7-hydroxy-delta-6-tetra-hydrocannabinol-dimethylheptyl i.e., HU-210 and HU-211.


Initially developed and/or characterized by Mechoulam et al., (1988), HU-210 and HU-211 are two of several diverse members of the HU-family that have attracted significant attention in the international research community. For instance, HU-210 has full agonist activity at CB1 and CB2, while the (+) enantiomer, i.e., HU-211 does not, but instead acts as via different pathways such as an N-Methyl-D-aspartate (NMDA) antagonist.


Other members that may offer clinical insights may include HU-308 (CB2 agonism), HU-331, HU-444, HU-580, HU-671, HU-910, HU-914.

Other Names:

HU Family Synthetic Cannabinoids

7-hydroxy-delta-6-tetra-hydrocannabinol-dimethylheptyl or 7-OH-delta-6-THC-DMH


HU-210 [(-)-enantiomer] (-)-7-OH-delta-6-THC-DMH (N. Titishov et al., 1989)



HU-211 [(+)-enantiomer]; (aka Dexanabinol) (+)-7-OH-delta-6-THC-DMH (N. Titishov et al., 1989)

HU-x Synthetic Cannabinoids Properties and Effects

Only Members can view Properties and Effects information. See DEMO page.

HU-x Synthetic Cannabinoids Receptor Binding

Only Members can view Receptor Binding information. See DEMO page.

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Information on this site is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your physician, nutritionally oriented health care practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications.