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5F-x Synthetic Cannabinoids Cannabinoid Research

5F-x Synthetic Cannabinoids Research Dashboard

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Overview - 5F-x Synthetic Cannabinoids

Description of 5F-x Synthetic Cannabinoids

5F-MDMB-PICA emerged as a novel "herbal" ingredient in drugs of the European recreational market in 2016 (under the names of e.g., "K2", "Spice") and was the most commonly available synthetic cannabinoid in the USA between 2019 and 2020. It is one of the more potent members and is associated with serious adverse health, behavioral effects and deaths.


Here we focus on 5F-MDMB-PICA.


Other potentially clinically relevant members may include 5F-AMBICA, 5F-AMB (full agonist at CB1), 5F-ADB, 5F-MDMB-PINACA.


5F-x class of synthetic cannabinoids are identified by their 5-flouropentyl chain.

Other Names:

5F-x Family of Synthetic Cannabinoids

5F-MDMB-PICA


IUPAC Name: methyl (2S)-2-[[1-(5-fluoropentyl)indole-3-carbonyl]amino]-3,3-dimethylbutanoate


Molecular Formula: C21H29FN2O3


Source–PubChem

5F-x Synthetic Cannabinoids Properties and Effects

Only Members can view Properties and Effects information. See DEMO page.

5F-x Synthetic Cannabinoids Receptor Binding

Only Members can view Receptor Binding information. See DEMO page.

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