Loss of Appetite Research Dashboard
Double-blind human trials
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CannaKeys has 16 studies associated with Loss of Appetite.
Here is a small sampling of Loss of Appetite studies by title:
- Cannabinoids in health and disease: pharmacological potential in metabolic syndrome and neuroinflammation
- Effects of cannabis use on body mass, fasting glucose and lipids during the first 12 months of treatment in schizophrenia spectrum disorders
- Got Munchies? Estimating the Relationship between Marijuana Use and Body Mass Index.
- Cannabinoid influences on palatability: microstructural analysis of sucrose drinking after delta(9)-tetrahydrocannabinol, anandamide, 2-arachidonoyl glycerol and SR141716
- Tetrahydrocannabinol and endocannabinoids in feeding and appetite
Components of the Loss of Appetite Research Dashboard
- Dosing information available for Loss of Appetite
- Chemotype guidance for treating Loss of Appetite with cannabis
- Synopsis of cannabis research for Loss of Appetite
- Individual study details for Loss of Appetite
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Overview - Loss of Appetite
Description of Loss of Appetite
The lack of appetite is defined by little interest in food. There are a number of physiological and psychological causes that can lead to having a poor appetite such as: chemotherapies, AIDS, stress, anorexia nervosa, stimulants (e.g. methamphetamines), or grief for example. As you can see some of these are self-correcting in time while the others tend to be of a chronic nature requiring assistance.
Loss of Appetite
Mental and Behavioural Disorders
ICD-10 Code: F50.89
Loss of Appetite Symptoms:
No interest in food, skinny, stress
Also known as:
Appetite Decreased, Poor Appetite
THC Interaction with Pharmaceutical Drugs
- THC can enhance the effects of drugs that cause sedation and depress the central nervous system, such as benzodiazepines, barbiturates, and alcohol, for example.
- THC is metabolized by and an inhibitor of a number of enzymatic liver pathways referred to as cytochrome P450. There are more than 50 enzymes belonging to this enzyme family, a number of which are responsible for the breakdown of common drugs such as antidepressants (e.g. amitriptyline, doxepine, fluvoxamine), antipsychotics (haloperidol, clozapine, stelazine), beta-blockers (e.g. propranolol), bronchodilators (e.g. theophylline), or bloodthinners (e.g. warfarin). Thus patients taking these classes of medication may find that THC increases the concentration and effects of these drugs as well as the duration of their effects.
- Clinical observation suggests no likely interactions with other pharmaceuticals at a total daily dose of up to 20mg THC.
CBD Interaction with Pharmaceutical Drugs
- CBD may alter action on metabolic enzymes (certain drug-transport mechanisms), and as such may alter interactions with other drugs, some of which may produce therapeutic or adverse effects. For instance, CBD interacts with the enzyme cytochrome P450 3A4 and cytochrome P450 2C19, increasing the bioavailability of anti-epileptic drugs such as clobazam (a benzodiazepine). This makes it possible to achieve the same results at significantly lower dosages, reducing treatment costs and risks of adverse effects.
- Groups of drugs affected include: anti-epileptic drugs, psychiatric drugs, and drugs affecting metabolic enzymes, for example.
- Clinical observations suggest no likely interactions with other pharmaceuticals at a total daily dose of up to 100mg CBD
THC Dosage Considerations
- THC micro dose: 0.1 mg to 0.4 mg
- THC low dose: 0.5 mg to 5 mg
- THC medium dose: 6 mg to 20 mg
- THC high dose: 21 mg to 50+ mg
CBD Dosage Considerations
- CBD low dose: 0.4 mg to 19 mg
- CBD medium dose: 20 mg to 99 mg
- CBD high dose: 100 mg to 800+ mg (upper limits tested ~1,500mg)
Disclaimers: Information on this site is provided for informational purposes only and is not meant to substitute for the advice provided by your own physician or other medical professional. You should not use the information contained herein for diagnosing a health problem or disease. If using a product, you should read carefully all product packaging. If you have or suspect that you have a medical problem, promptly contact your health care provider.
Information on this site is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your physician, nutritionally oriented health care practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications.