Cardiac Arrhythmias – Cannabis Research

Cardiac Arrhythmias Research Dashboard


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CannaKeys has 45 studies associated with Cardiac Arrhythmias.

Here is a small sampling of Cardiac Arrhythmias studies by title:

Components of the Cardiac Arrhythmias Research Dashboard

  • Dosing information available for Cardiac Arrhythmias
  • Chemotype guidance for treating Cardiac Arrhythmias with cannabis
  • Synopsis of cannabis research for Cardiac Arrhythmias
  • Individual study details for Cardiac Arrhythmias

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Overview - Cardiac Arrhythmias

Description of Cardiac Arrhythmias

The term arrhythmias are derived by combining the Greek word a- meaning “not” and the word rhythmos meaning “symmetry” or “proportion.” Cardiac arrhythmias occur when the electrical impulses of the heart that instruct the heart muscles to work in symmetry are not working properly resulting in inefficient heart function which in turn can cause a variety of signs and symptoms that range somewhere in between mild and fatal.

Disease Classification

Condition: Cardiac Arrhythmias
Disease Family: Deficiency Disorder
Organ System: Cardiovascular System
ICD-10 Chapter: Diseases of the Circulatory System
ICD-10 Code: I49

Cardiac Arrhythmias Symptoms:

Irregular heartbeat, angina, palpitation (feeling skipped beats), depending on severity may include anxiety, dizzyness, chest pain, shortness of breath, paleness, diaphoresis, cold clammy extremities, nausea and vomiting, loss of consciousness, respiratory arrest, myocardial infarction (heart attack) and death.

Also known as:

Cardiac Dysrhythmias: Atrial Tachycardia, A-flutter, A-fibrillation, Wolff-Parkinson-White syndrome, Paroxysmal Supraventricular Tachycardia (PSVT); Bradycardia; Ventricular Dysrhythmias, V-tachycardia (VT), Premature Ventricular Contractions (PVC), Ventricular Fibrillation (V-Fib), Ventricular Ectopy, Premature Ventricular Contractions, Widening QT syndrome

Drug Interactions

THC Interaction with Pharmaceutical Drugs

  • THC can enhance the effects of drugs that cause sedation and depress the central nervous system, such as benzodiazepines, barbiturates, and alcohol, for example. 
  • THC is metabolized by and an inhibitor of a number of enzymatic liver pathways referred to as cytochrome P450. There are more than 50 enzymes belonging to this enzyme family, a number of which are responsible for the breakdown of common drugs such as antidepressants (e.g. amitriptyline, doxepine, fluvoxamine), antipsychotics (haloperidol, clozapine, stelazine), beta-blockers (e.g. propranolol), bronchodilators (e.g. theophylline), or bloodthinners (e.g. warfarin).  Thus patients taking these classes of medication may find that THC increases the concentration and effects of these drugs as well as the duration of their effects.
  • Clinical observation suggests no likely interactions with other pharmaceuticals at a total daily dose of up to 20mg THC.

CBD Interaction with Pharmaceutical Drugs

  • CBD may alter action on metabolic enzymes (certain drug-transport mechanisms), and as such may alter interactions with other drugs, some of which may produce therapeutic or adverse effects. For instance, CBD interacts with the enzyme cytochrome P450 3A4 and cytochrome P450 2C19, increasing the bioavailability of anti-epileptic drugs such as clobazam (a benzodiazepine). This makes it possible to achieve the same results at significantly lower dosages, reducing treatment costs and risks of adverse effects. 
  • Groups of drugs affected include: anti-epileptic drugs, psychiatric drugs, and drugs affecting metabolic enzymes, for example.
  • Clinical observations suggest no likely interactions with other pharmaceuticals at a total daily dose of up to 100mg CBD

Dosing Considerations

THC Dosage Considerations

  • THC micro dose:  0.1 mg to 0.4 mg
  • THC low dose:  0.5 mg to 5 mg
  • THC medium dose:  6 mg to 20 mg
  • THC high dose:  21 mg to 50+ mg

CBD Dosage Considerations

  • CBD low dose:  0.4 mg to 19 mg
  • CBD medium dose: 20 mg to 99 mg
  • CBD high dose:  100 mg to 800+ mg (upper limits tested ~1,500mg)

Disclaimers: Information on this site is provided for informational purposes only and is not meant to substitute for the advice provided by your own physician or other medical professional. You should not use the information contained herein for diagnosing a health problem or disease. If using a product, you should read carefully all product packaging. If you have or suspect that you have a medical problem, promptly contact your health care provider.

Information on this site is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your physician, nutritionally oriented health care practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications.