Excessive Vomiting in Pregnancy Research Dashboard
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CannaKeys has 19 studies associated with Excessive Vomiting in Pregnancy.
Here is a small sampling of Excessive Vomiting in Pregnancy studies by title:
- Patterns of Use and Self-reported Effectiveness of Cannabis for Hyperemesis Gravidarum
- The use of cannabis for Hyperemesis Gravidarum (HG)
- Plasma anandamide and related n-acylethanolamide levels are not elevated in pregnancies complicated by hyperemesis gravidarum
- Marijuana Use and Maternal Experiences of Severe Nausea During Pregnancy in Hawai‘i
- Survey of medicinal cannabis use among childbearing women: patterns of its use in pregnancy and retroactive self-assessment of its efficacy against \'morning sickness\'.
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- Chemotype guidance for treating Excessive Vomiting in Pregnancy with cannabis
- Synopsis of cannabis research for Excessive Vomiting in Pregnancy
- Individual study details for Excessive Vomiting in Pregnancy
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Overview - Excessive Vomiting in Pregnancy
Description of Excessive Vomiting in Pregnancy
An estimated 50% of all pregnant women develop some kind of morning sickness, usually starting in the middle of the first trimester (at about six weeks). Normally, these episodes of nausea and vomiting are self-limiting and disappear toward the end of the first trimester (three months). While women can experience nausea and vomiting at any time of the day, these symptoms more commonly occur in the morning hours. Vomiting with serious loss of fluid (more than 5% of pre-pregnancy body weight) meets the diagnosis criteria for hyperemesis gravidarum, which may require hospitalisation and IV-fluid/electrolyte replacements.
Pregnancy, childbirth and the puerperium
ICD-10 Code: 021.9
Excessive Vomiting in Pregnancy Symptoms:
Nausea, nausea with vomiting, nausea/vomiting triggered by certain scents, heightened senses of smell and taste
Also known as:
Excessive vomiting in pregnancy, vomiting in pregnancy, hyperemesis gravidarum (i.e., if vomiting in pregnancy is severe enough to cause 5% fluid loss)
THC Interaction with Pharmaceutical Drugs
- THC can enhance the effects of drugs that cause sedation and depress the central nervous system, such as benzodiazepines, barbiturates, and alcohol, for example.
- THC is metabolized by and an inhibitor of a number of enzymatic liver pathways referred to as cytochrome P450. There are more than 50 enzymes belonging to this enzyme family, a number of which are responsible for the breakdown of common drugs such as antidepressants (e.g. amitriptyline, doxepine, fluvoxamine), antipsychotics (haloperidol, clozapine, stelazine), beta-blockers (e.g. propranolol), bronchodilators (e.g. theophylline), or bloodthinners (e.g. warfarin). Thus patients taking these classes of medication may find that THC increases the concentration and effects of these drugs as well as the duration of their effects.
- Clinical observation suggests no likely interactions with other pharmaceuticals at a total daily dose of up to 20mg THC.
CBD Interaction with Pharmaceutical Drugs
- CBD may alter action on metabolic enzymes (certain drug-transport mechanisms), and as such may alter interactions with other drugs, some of which may produce therapeutic or adverse effects. For instance, CBD interacts with the enzyme cytochrome P450 3A4 and cytochrome P450 2C19, increasing the bioavailability of anti-epileptic drugs such as clobazam (a benzodiazepine). This makes it possible to achieve the same results at significantly lower dosages, reducing treatment costs and risks of adverse effects.
- Groups of drugs affected include: anti-epileptic drugs, psychiatric drugs, and drugs affecting metabolic enzymes, for example.
- Clinical observations suggest no likely interactions with other pharmaceuticals at a total daily dose of up to 100mg CBD
THC Dosage Considerations
- THC micro dose: 0.1 mg to 0.4 mg
- THC low dose: 0.5 mg to 5 mg
- THC medium dose: 6 mg to 20 mg
- THC high dose: 21 mg to 50+ mg
CBD Dosage Considerations
- CBD low dose: 0.4 mg to 19 mg
- CBD medium dose: 20 mg to 99 mg
- CBD high dose: 100 mg to 800+ mg (upper limits tested ~1,500mg)
Disclaimers: Information on this site is provided for informational purposes only and is not meant to substitute for the advice provided by your own physician or other medical professional. You should not use the information contained herein for diagnosing a health problem or disease. If using a product, you should read carefully all product packaging. If you have or suspect that you have a medical problem, promptly contact your health care provider.
Information on this site is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your physician, nutritionally oriented health care practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications.