Cervical Cancer Research Dashboard
What am I missing as a non-subscriber?
To see a full dashboard with study details and filtering, go to our DEMO page.
As a subscriber, you will be able to access dashboard insights including chemotype overviews and dosing summaries for medical conditions and organ system and receptor breakdowns for cannabinoid and terpene searches. Study lists present important guidance including dosing and chemotype information with the ability to drill down to the published material. And all outputs are fully filterable, to help find just the information you need. Stay up-to-date with the science of cannabis and the endocannabinoid system with CannaKeys.
CannaKeys has 20 studies associated with Cervical Cancer.
Here is a small sampling of Cervical Cancer studies by title:
- Inhibition of monoacylglycerol lipase restrains proliferation, migration, invasion, tumor growth and induces apoptosis in cervical cancer
- Prescribed medical cannabis in women with gynecologic malignancies: A single-institution survey-based study
- Cannabidiol Rather Than Cannabis Sativa Extracts Inhibit Cell Growth And Induce Apoptosis In Cervical Cancer Cells
- Marijuana Use is Not Associated with Cervical Human Papillomavirus Natural History or Cervical Neoplasia in HIV-seropositive or HIV-seronegative Women
- Cannabidiol Inhibits Cancer Cell Invasion Via Upregulation Of Tissue Inhibitor Of Matrix Metalloproteinases-1
Components of the Cervical Cancer Research Dashboard
- Dosing information available for Cervical Cancer
- Chemotype guidance for treating Cervical Cancer with cannabis
- Synopsis of cannabis research for Cervical Cancer
- Individual study details for Cervical Cancer
Ready to become a subscriber? Go to our PRICING page.
Cervical Cancer Research Dashboard
What am I missing as a non-subscriber?
To see a full dashboard with study details and filtering, go to our DEMO page.
As a subscriber, you will be able to access dashboard insights including chemotype overviews and dosing summaries for medical conditions and organ system and receptor breakdowns for cannabinoid and terpene searches. Study lists present important guidance including dosing and chemotype information with the ability to drill down to the published material. And all outputs are fully filterable, to help find just the information you need. Stay up-to-date with the science of cannabis and the endocannabinoid system with CannaKeys.
CannaKeys has 20 studies associated with Cervical Cancer.
Here is a small sampling of Cervical Cancer studies by title:
- Inhibition of monoacylglycerol lipase restrains proliferation, migration, invasion, tumor growth and induces apoptosis in cervical cancer
- Prescribed medical cannabis in women with gynecologic malignancies: A single-institution survey-based study
- Cannabidiol Rather Than Cannabis Sativa Extracts Inhibit Cell Growth And Induce Apoptosis In Cervical Cancer Cells
- Marijuana Use is Not Associated with Cervical Human Papillomavirus Natural History or Cervical Neoplasia in HIV-seropositive or HIV-seronegative Women
- Cannabidiol Inhibits Cancer Cell Invasion Via Upregulation Of Tissue Inhibitor Of Matrix Metalloproteinases-1
Components of the Cervical Cancer Research Dashboard
- Dosing information available for Cervical Cancer
- Chemotype guidance for treating Cervical Cancer with cannabis
- Synopsis of cannabis research for Cervical Cancer
- Individual study details for Cervical Cancer
Ready to become a subscriber? Go to our PRICING page.
Select New Condition
Overview - Cervical Cancer
Description of Cervical Cancer
The term ”cervix” is Latin for neck. Cancer of the cervix uteri is the development of cancerous cells at the narrow neck of the uterus. The cervix starts with the external os at the end of the vagina and continues inward through the endocervical canal until it forms the internal os. Nearly all cervical cancers start in the ecto- or endocervical mucosa in the transformation zone between old and new squamocolumnar epithelium.
Meanwhile, the uterus begins at the interior end of the vagina and together with the cervix, fallopian tubes, birth canal, and ovaries, comprise the female reproductive system.
Thus, cervical cancer can be better visualized and monitored and may require more straightforward outpatient treatments. However, prevention through HPV vaccination and routine screening represent public health measures against cervical cancer. HPV infection is associated with the overwhelming majority of cases (>70%) of cervical cancer.
Orthodox medicine hypothesizes numerous possible causes and co-factors for the development of cervical cancer among higher-risk persons born female. Higher risk is defined by the presence of statistically significant co-factors, such as a family history of cervical cancer, poverty, substance abuse, socioeconomic factors, human papillomavirus (HPV) infection, lack of HPV vaccination, HIV/AIDS, herpes simplex, and use of pharmaceutical birth control (this is not well understood).
Other factors include a weakened immune system, tobacco smoking or secondhand smoke, obesity, multiple prior pregnancies, dietary factors, and a high number of sex partners or risky sex behaviors. An unusual exposure to diethylstilbestrol (DES), a pregnancy pharmaceutical given from 1940-71, is a rare but significant risk factor for cervical cell abnormalities and clear cell adenocarcinoma in children of people who took this drug.
Disease Classification
Condition: Cancer - CervicalDisease Family: Cancer
Organ System: Reproductive System
ICD-10 Chapter: Neoplasms
ICD-10 Code: C53
Cervical Cancer Symptoms:
Unusual bloody vaginal discharge (such as in between periods, after sex, after menopause), painful vaginal intercourse, watery or bloody discharge with a foul odor. In advanced stages, chronic pelvic pain, difficulty with urination or bowel movements, fatigue, leg swelling, backache, or blood in the urine or stool may occur.Also known as:
Malignant Neoplasm of the Cervix UteriDrug Interactions
THC Interaction with Pharmaceutical Drugs
- Tetrahydrocannabinol (THC) can enhance the effects of drugs that cause sedation and depress the central nervous system, such as benzodiazepines, barbiturates, and alcohol.
- THC is metabolized by an inhibitor of several enzymatic liver pathways referred to as cytochrome P450 (aka CYP450). There are more than 50 enzymes belonging to this enzyme family, several of which are responsible for the breakdown of common drugs such as antidepressants (e.g., amitriptyline, doxepin, fluvoxamine), antipsychotics (haloperidol, clozapine, Stelazine), beta-blockers (e.g., propranolol), bronchodilators (e.g., theophylline), or blood thinners (e.g., warfarin). Thus, patients taking these medication classes may find that THC increases the concentration and effects of these drugs and the impact duration.
- Clinical observation (not yet confirmed by clinical trials) suggests no likely interactions with other pharmaceuticals at a total daily dose of up to 20mg THC.
If you are interested in the interaction potential of specific pharmaceuticals with THC, consider visiting these free drug interaction checkers: Drugs.com or DrugBank Online.
CBD Interaction with Pharmaceutical Drugs
- Cannabidiol (CBD) may alter the action of metabolic enzymes (specific drug-transport mechanisms) and alter interactions with other drugs, some of which may produce therapeutic or adverse effects. For instance, CBD interacts with the enzyme cytochrome P450 3A4 and cytochrome P450 2C19, increasing the bioavailability of anti-epileptic drugs such as clobazam (a benzodiazepine). This makes it possible to achieve the same results at significantly lower dosages, reducing treatment costs and risks of adverse effects.
- Groups of drugs affected include anti-epileptics, psychiatric drugs, and drugs affecting metabolic enzymes.
- Clinical observations (not yet confirmed by clinical trials) suggest no likely interactions with other pharmaceuticals at a total daily dose of up to 100mg CBD.
If you are interested in the interaction potential of specific pharmaceuticals with CBD, consider visiting these free drug interaction checkers: Drugs.com or DrugBank Online.
THC/CBD Interaction with Pharmaceutical Drugs
In general, when using cannabinoid-based therapeutics that contain both THC and CBD consider the ratio between them and weigh the relevant information displayed in the individual THC and CBD Drug Interaction windows accordingly.
If you are interested in the interaction potential of specific pharmaceuticals with both primary cannabinoids and THC/CBD, consider visiting these free drug interaction checkers: Drugs.com or DrugBank Online.
Concerns about Cannabis and Cancer-related Immunotherapies:
Some recent clinical observational studies have suggested that the co-administration of cannabinoid-based therapeutics and immunotherapy or immune checkpoint inhibitors in the treatment of certain types of cancer has been associated with worse overall survival rates (T. Taha et al., 2019; A. Biedny et al., 2020; G. Bar-Sela et al., 2020).
However, other studies have suggested that the co-commitment use of immune checkpoint inhibitors and cannabis-induced no such deleterious effects. More specifically, one trial was conducted on animals resulting in data suggesting that cannabis did not negatively affect the properties of immune checkpoint inhibitors (B. Waissengrin et al., 2023). The same authors compared the previous study results with findings from a cohort of 201 patients with metastatic non-small cell lung cancer who received treatment with monotherapy pembrolizumab as a first-line treatment and adjunct cannabis to treat mainly pain and loss of appetite. Their time to tumor progression was 6.1 versus 5.6 months, and overall survival differed between 54.9 versus 23.6 months in cannabis-naïve patients and cannabis-using patients, respectively. However, while numerically different, the authors write that these differences were not statistically significant, leading them to suggest that “These data provide reassurance regarding the absence of a deleterious effect of cannabis in this clinical setting.”
Dosing Considerations
THC Dosage Considerations
- THC micro dose: 0.1 mg to 0.4 mg
- THC low dose: 0.5 mg to 5 mg
- THC medium dose: 6 mg to 20 mg
- THC high dose: 21 mg to 50+ mg
CBD Dosage Considerations
- CBD low dose: 0.4 mg to 19 mg
- CBD medium dose: 20 mg to 99 mg
- CBD high dose: 100 mg to 800+ mg (upper limits tested ~1,500mg)
Disclaimer
Information on this site is provided for informational purposes only and is not meant to substitute for the advice provided by your own licensed physician or other medical professional. You
should not use the information contained herein for diagnosing or treating a health problem or disease. If using a product, you should read carefully all product packaging. If you have or suspect that you have a
medical problem, promptly contact your health care provider.
Information on this site is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your physician, nutritionally oriented health care practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications.
