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Terpineol – Terpenes and Cannabinoid Research

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Overview - Terpineol

What is Terpineol?

Terpineol is a scent and flavoring agent in foods, perfumes, cosmetics, and cleaning products.


Alpha-terpineol has been shown to enhance skin's permeability to lipid-soluble compounds, which may help create a topical entourage effect with lipophilic cannabinoids. For instance, if a patient would like to employ the anti-acne effects of the lipophilic cannabinoid CBD combining it with a small amount of terpineol may enhance localized bioavailability and, as such better possible therapeutic results.


Is Terpineol safe?


Isolated alpha-terpineol appearance ranges from a colorless viscous liquid to a solid and may irritate skin, eyes, and mucous membranes.

Other Names

IUPAC Name (alpha-terpineol): 2-(4-methylcyclohex-3-en-1-yl)propan-2-ol


Source–PubChem

Scent Description

Lilac, pine, citrus, woody, floral

Natural Sources

Pine trees, tea tree oil, limes

Cannabis Cultivars High in Terpineol

Jack Herer, White Widow, Girl Scout Cookies, OG Kush

Terpineol Properties and Effects

Terpineol is associated with the following properties and effects:



  1.  Analgesic (E. Liktor-Busa et al., 2021)

    1. Anti-inflammatory pain (E. Liktor-Busa et al., 2021)

    2. Nociceptive pain (S. Parvardeh et al., 2016)



  2. Anti-addictive (opioids) (S. Parvardeh et al., 2016)

  3. Antibacterial

  4. Anticancer

  5. Anti-fungal

Terpineol Receptor Binding

Endocannabinoid System (ECS) and Terpineol:



  1. CB1 (agonist) (N. Raz et al., 2023)


Endocannabinoidome (eCBome) and Terpineol:

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Disclaimer
Information on this site is provided for informational purposes only and is not meant to substitute for the advice provided by your own licensed physician or other medical professional. You should not use the information contained herein for diagnosing or treating a health problem or disease. If using a product, you should read carefully all product packaging. If you have or suspect that you have a medical problem, promptly contact your health care provider.

Information on this site is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your physician, nutritionally oriented health care practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications.