Omega-6 Research Dashboard
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Overview - Omega-6
Description of Omega-6
Polyunsaturated fatty acids (PUFAs) are essential building blocks. Since the human body does not make its own PUFAs, we must consume them to survive and thrive. PUFAs such as omega-6 (and omega-3) fatty acids are primary building blocks the body uses to make its own endocannabinoids. And, omega-6-based endocannabinoids are considered multi-functional molecules acting at various receptor sites.
Anandamide (AEA) and 2-arachidonoylglycerol (2-AG) are made from arachidonic acid (ARA), the more abundant omega-6 (n6) in the brain. Levels of ARA determine the levels of 2-AG and AEA. Western diet a high ratio of n6:n3 may lead to an overstimulation of the ECS resulting in increased neuroinflammation, neurodegeneration, and pathological aging (S. Dyall 2017).
However, here is an important insight: a healthy ECS is dependent on the ratio of omega-3 to omega-6.
Other Names:
Arachidonic acid (ARA)IUPAC name: (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid (plus numerous other supplier-based synonyms)
Source–PubChem
Omega-6 Properties and Effects
Only Members can view Properties and Effects information. See DEMO page.
Omega-6 Receptor Binding
Only Members can view Receptor Binding information. See DEMO page.
Disclaimer
Information on this site is provided for informational purposes only and is not meant to substitute for the advice provided by your own licensed physician or other medical professional. You
should not use the information contained herein for diagnosing or treating a health problem or disease. If using a product, you should read carefully all product packaging. If you have or suspect that you have a
medical problem, promptly contact your health care provider.
Information on this site is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your physician, nutritionally oriented health care practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications.
