Limonene – Terpenes and Cannabinoid Research

Limonene Research Dashboard


Primary Studies


Related Studies


Total Studies

Clinical Studies


Clinical Meta-analyses


Double-blind human trials


Clinical human trials

Pre-Clinical Studies




Animal studies


Laboratory studies

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As a subscriber, you will be able to access dashboard insights including chemotype overviews and dosing summaries for medical conditions and organ system and receptor breakdowns for cannabinoid and terpene searches. Study lists present important guidance including dosing and chemotype information with the ability to drill down to the published material. And all outputs are fully filterable, to help find just the information you need. Stay up-to-date with the science of cannabis and the endocannabinoid system with CannaKeys.

CannaKeys has 52 studies associated with Limonene.

Here is a small sampling of Limonene studies by title:

Components of the Limonene Research Dashboard

  • Top medical conditions associated with Limonene
  • Proven effects in clinical trials for Limonene
  • Receptors associated with Limonene
  • Individual study details for Limonene

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Overview - Limonene


Limonene is the second most abundant terpene in nature after pinene. Upon inhalation, limonene becomes rapidly bioavailable in humans. Limonene is the precursor of perillyl alcohol, a common monoterpene found in various citrus fruits and essential oils.

Description of Limonene and Cautions

The terpene limonene is a clear, colorless liquid and has been given GRAS (generally recognized as safe) status though the isolated orm may cause skin irritation and serious eye iritation.

Scent Description

Lemon, citrus, orange, turpentine

Natural Sources

Citrus, juniper, lemons, limes, oranges

Summary of Limonene Effects

May protect against breast and skin cancers, antioxidant, may reduce obesity and reduce weight loss, antifungal, anti-inflammatory (bronchial asthma), may help with cholesterol-based gallbladder stones, may normalize peristalsis in cases of heartburn and GERD.

Cannabis Strains High in Limonene

Sour Diesel, Bruce Banner, Marionberry, OG Glue, Animal Cookies

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Information on this site is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your physician, nutritionally oriented health care practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications.