Key Findings:  Results showed that the 1 : 4 mixture of lupenone and caryophyllene oxide is active in the chronic phase of the disease, reducing significantly the number of amastigote nests in both cardiac tissue and skeletal muscle. In addition, testing of the terpenoid mixture for its capacity to reduce the number of amastigote nests in cardiac tissue and skeletal muscle of infected mice showed a reduction of more than 80% at a dose level of 20.8 mg·kg−1·day−1.
Type of Study:  Animal Study
Study Result:  Positive
Study Location(s):  Bolivia, Mexico
Year of Pub:  2013
Cannabinoids Studied: 
Phytocannabinoid Source:  Not Applicable
Terpenes Studied:  ß-Caryophyllene