PRIMARY STUDY

Cannabinoid Receptor 1 Blockade Ameliorates Albuminuria in Experimental Diabetic Nephropathy.

Key Findings:  In experimental type 1 diabetes, the CB1 receptor is overexpressed by glomerular podocytes, and blockade of the CB1 receptor (via AM-251) ameliorates albuminuria possibly via prevention of nephrin, podocin, and ZO-1 loss.

Type of Study:  Animal Study

Study Result:  Positive

Study Location(s):  Italy

Year of Pub:  2012


Cannabinoids Studied:  AM-x Synthetic Cannabinoids

Phytocannabinoid Source:  Not Applicable