Key Findings:  Through these direct mechanisms or through indirect mechanisms involving GABA or glutamate neurons, cannabinoids may interact with dopaminergic transmission in the basal ganglia and this is likely to have important effects on dopamine-related functions in these structures (i.e. control of movement) and, particularly, on different pathologies affecting these processes, in particular, Parkinson's disease, but also dyskinesia, dystonia and other pathological conditions.
Type of Study:  Meta-analysis
Study Result:  Positive
Study Location(s):  Spain
Year of Pub:  2016
Cannabinoids Studied:  Tetrahydrocannabinol (THC), AM-x Synthetic Cannabinoids, WIN-x Synthetic Cannabinoids, Anandamide (AEA), Fatty Acid Amide Hydrolase (FAAH), 2-Arachidonoyl Glycerol (2-AG), Monoacylglycerol Lipase (MAGL), Cannabinoid (unspecified), Other Related Compounds
Phytocannabinoid Source:  Not Applicable
Receptors Studied:  CB1, CB2, TRPV1, PPAR - Alpha, PPAR - Gamma
Ligands Studied:  Dopamine, GABA, Glutamate