PRIMARY STUDY

Effect of Dipeptidyl Peptidase-4 (DPP-4) Inhibition on Biomarkers of Kidney Injury and Vascular Calcification in Diabetic Kidney Disease: A Randomized Controlled Trial

Key Findings:  Among patients with diabetes who were given gemigliptin, compared to placebo there were significant improvements in biomarkers of vascular and renal function, including improved levels of liver fatty acid-binding protein (L-FABP)/Cr.

Type of Study:  Clinical Trial

Study Sample Size:  182

Study Result:  Positive

Study Location(s):  Thailand

Year of Pub:  2021


Cannabinoids Studied:  Fatty Acid-Binding Protein (FABP)

Phytocannabinoid Source:  Not Applicable

Ligands Studied:  Insulin, Pro-inflammatory cytokines