PRIMARY STUDY

Implications of the endocannabinoid system and the therapeutic action of cannabinoids in autism spectrum disorder: A literature review

Key Findings:  This review of the current literature on the role of the endocannabinoid system (ECS) and the use of cannabidiol (CBD) in the treatment of patients with Autism spectrum disorder (ASD) concludes that: CBD in pure form is useful in treating symptoms and comorbidities of ASD, can regulate several different neurotransmitters, and can modulate endogenous ligands, enzymes, and membrane transporters of the ECS.

Type of Study:  Meta-analysis

Study Result:  Positive

Study Location(s):  Brazil

Year of Pub:  2022


Cannabinoids Studied:  Cannabidiol (CBD)

Phytocannabinoid Source:  Isolate

Chemotype:  Chemotype III

Ligands Studied:  Dopamine, GABA, Glutamate, Serotonin