DOSING DETAILS   

Study Dosing Objective:  Effective Dose

Established Protocol:  Effective dose

Route of Administration: 

Cannabinoid Ratio:  (CBC)   0    

Dosing Regimen:  CBC (1 μM) CBC significantly cured experimental colitis at the 1 mg/kg daily dose CBC had statistically significant pharmacological actions starting from the 10 mg/kg dose

Treatment Duration:  30 minutes

Clinical Relevance:  It appears feasible that cannabichromene (CBC) may limit tissue destruction caused by nitric oxide (NO) in autoimmune diseases by decreasing NO production. There is also evidence based on its curative effect on murine colitis in vivo, CBC is a promising candidate for clinical evaluation in inflammatory bowel disease.

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