RELATED STUDY

The endocannabinoidome as a substrate for noneuphoric phytocannabinoid action and gut microbiome dysfunction in neuropsychiatric disorders


Key Findings:  The authors highlight the role the eCBome plays in the microbiota-gut-brain axis and its association with affective and cognitive functions and in their pathological alterations in neuropsychiatric disorders.
 In addition, the review focuses on eCBome-based drugs beyond that of THC including CBD, which possess a wide therapeutic window.

Type of Study:  Meta-analysis

Study Result:  Positive

Research Location(s):  Italy

Year of Pub:  2020


Cannabinoids Studied:  Cannabidiol (CBD), Tetrahydrocannabinol (THC), Microbiome

Phytocannabinoid Source:  Unspecified

Receptors Studied:  CB1, CB2




Citation:  Di Marzo V. The endocannabinoidome as a substrate for noneuphoric phytocannabinoid action and gut microbiome dysfunction in neuropsychiatric disorders
. Dialogues Clin Neurosci. 2020; 22:259-269. doi: 10.31887/DCNS.2020.22.3/vdimarzo

Authors:  Di Marzo V