PRIMARY STUDY
β-Caryophyllene, a CB2 Receptor-Selective Phytocannabinoid, Suppresses Motor Paralysis and Neuroinflammation in a Murine Model of Multiple Sclerosis.
Key Findings: The study represents significant implications for clinical research and strongly supports the effectiveness of β-Caryophyllene as a novel molecule to target in the development of effective therapeutic agents for MS.
Type of Study: Animal Study
Study Result: Positive
Study Location(s): Brazil
Year of Pub: 2017
Cannabinoids Studied: AM-x Synthetic Cannabinoids, JWH-x Synthetic Cannabinoids
Phytocannabinoid Source: Not Applicable
Terpenes Studied: ß-Caryophyllene
Receptors Studied: CB2
Ligands Studied: Anti-inflammatory cytokines, Pro-inflammatory cytokines
Dosage: BCP (25 or 50 mg/kg)