RELATED STUDY
Anti-Inflammatory and Pro-Autophagy Effects of the Cannabinoid Receptor CB2R: Possibility of Modulation in Type 1 Diabetes
Key Findings: This review discusses how CB1R and CB2R are involved in regulating the inflammasome and the release of the cytokine interleukin 1B (IL-1β). CB2R activation controls intracellular self-death and may help regulate the secretion of extracellular vesicles which induces chronic inflammation and obesity, especially as in type1 diabetes mellitus.
Type of Study: Meta-analysis
Study Result: Positive
Study Location(s): United States
Year of Pub: 2021
Cannabinoids Studied: Cannabidiol (CBD), Tetrahydrocannabinol (THC), AM-x Synthetic Cannabinoids, JWH-x Synthetic Cannabinoids, HU-x Synthetic Cannabinoids, Anandamide (AEA), 2-Arachidonoyl Glycerol (2-AG), Endocannabinoid (unspecified)
Phytocannabinoid Source: Unspecified
Terpenes Studied: ß-Caryophyllene
Receptors Studied: CB1, CB2
Ligands Studied: Anti-inflammatory cytokines, Serotonin, Pro-inflammatory cytokines
