Key Findings:  In this rat model of insulin resistance and type 2 diabetes, co-treatment with β-Caryophyllene showed increased both protein and mRNA expression of insulin receptors. This could lead to future therapeutic uses in the treatment and management of type 2 diabetes.
Type of Study:  Animal Study
Study Result:  Positive
Research Location(s):  India
Year of Pub:  2021
Cannabinoids Studied: 
Phytocannabinoid Source:  Not Applicable
Terpenes Studied:  ß-Caryophyllene
Ligands Studied:  Insulin
Route of Administration:  Oral (Ingestion)
Citation:  Mani V, et al. Effect of β-Caryophyllene on insulin resistance in skeletal muscle of high fat diet and fructose-induced type-2 diabetic rats. Bioinformation. 2021; 17:741-747. doi: 10.6026/97320630017741
Authors:  Mani V, Badrachalam R, Shanmugam SN, Balraj M, Kasthuri R, Danavel A, Babu S