PRIMARY STUDY

Anticonvulsant activity of β-caryophyllene in association with pregabalin in a seizure model in rats

Key Findings:  This study evaluating a rat model of epilepsy found that beta-caryophyllene plus pregabalin extended the time of onset of seizures, both myoclonic and tonic-clonic, and reduced the duration of tonic-clonic seizures and overall score. This suggests a potential synergistic approach to the treatment of drug-resistant seizure types.