PRIMARY STUDY

β-Caryophyllene attenuates lipopolysaccharide-induced acute lung injury via inhibition of the MAPK signalling pathway

Key Findings:  Resulting data revealed that BCP protects against inflammatory responses. The authors posit that BCP is a potentially novel therapeutic compound for the treatment of lipopolysaccharide-induced acute lung injury.

Type of Study:  Animal Study

Study Result:  Positive

Research Location(s):  China

Year of Pub:  2021


Cannabinoids Studied: 

Phytocannabinoid Source:  Not Applicable

Terpenes Studied:  ß-Caryophyllene

Ligands Studied:  Anti-inflammatory cytokines, Pro-inflammatory cytokines




Citation:  Zhang Y, et al. β-Caryophyllene attenuates lipopolysaccharide-induced acute lung injury via inhibition of the MAPK signalling pathway. J Pharm Pharmacol. 2021; 73:1319-1329. doi: 10.1093/jpp/rgab074

Authors:  Zhang Y, Zhang H, Li Y, Wang M, Qian F