PRIMARY STUDY
β-caryophyllene, an FDA-Approved Food Additive, Inhibits Methamphetamine-Taking and Methamphetamine-Seeking Behaviors Possibly via CB2 and Non-CB2 Receptor Mechanisms
Key Findings: Resulting data revealed that BCP reduces METH reward, METH intake, and motivation to seek and take METH via via modulation of both CB2- and non-CB2-dependent mechanisms.
Type of Study: Animal Study
Study Result: Positive
Research Location(s): China, United States
Year of Pub: 2021
Cannabinoids Studied:
Phytocannabinoid Source: Not Applicable
Terpenes Studied: ß-Caryophyllene
Receptors Studied: CB2
Route of Administration: Injection
Citation: He XH, et al. β-caryophyllene, an FDA-Approved Food Additive, Inhibits Methamphetamine-Taking and Methamphetamine-Seeking Behaviors Possibly via CB2 and Non-CB2 Receptor Mechanisms. Front Pharmacol. 2021; 12:722476. doi: 10.3389/fphar.2021.722476
Authors: He XH, Galaj E, Bi GH, He Y, Hempel B, Wang YL, Gardner EL, Xi ZX
