Phytocannabinoids in Neurological Diseases: Could They Restore a Physiological GABAergic Transmission?

Key Findings:  Endocannabinoids and phytocannabinoids (e.g. THC, CBD) and their interaction capacity to modulate GABA type A receptor function makes them a novel class of compounds of interest for a wide range of patient populations with various neurological conditions.

Type of Study:  Meta-analysis

Study Result:  Inconclusive

Study Location(s):  Italy, Netherlands

Year of Pub:  2020

Cannabinoids Studied:  Cannabidiol (CBD), Tetrahydrocannabinol (THC)

Phytocannabinoid Source:  Unspecified

Ligands Studied:  GABA