PRIMARY STUDY

Oral Cannabidiol Use in Children With Autism Spectrum Disorder to Treat Related Symptoms and Co-morbidities

Key Findings:  Pediatric patients with ASD received CBD (oil) for an average duration of 66 days. Specific reports indicate that self-injury and rage attacks improved in 67.6% and worsened in 8.8%. Hyperactivity symptoms improved in 68.4%. Sleep problems improved in 71.4% and worsened in 4.7%. Anxiety improved in 47.1% and worsened in 23.5%. Noted adverse effects included somnolence and change in appetite were mild.

Type of Study:  Clinical Trial

Study Sample Size:  53

Study Result:  Positive

Study Location(s):  Israel

Year of Pub:  2019


Cannabinoids Studied:  Cannabidiol (CBD), Tetrahydrocannabinol (THC)

Phytocannabinoid Source:  Not Applicable

Chemotype:  Chemotype III

Sub-Ratio: 1:20 (THC:CBD)

Dosage: CBD (Recommended daily dose of 16 mg/kg (maximal daily dose 600 mg), and THC (daily dose of 0.8 mg/kg (maximal daily dose of 40 mg))

Route of Administration:  Oral (Ingestion)



Link to study