Key Findings:  The results revealed decreased diastolic blood pressure, increased heart rate, and significant increased skin temperature. The subjects described themselves as more energetic, relaxed, and calm. These results suggest that the brain wave activity and ANS are affected by the inhalation of the EO of Cannabis sativa suggesting a neuromodular activity in cases of stress, depression, and anxiety.
Type of Study:  Double Blind Clinical Trial
Study Sample Size:  5
Study Result:  Positive
Research Location(s):  Italy
Year of Pub:  2018
Cannabinoids Studied:  Cannabidiol (CBD), Tetrahydrocannabinol (THC)
Phytocannabinoid Source:  Hemp derived
Terpenes Studied:  ß-Caryophyllene, Myrcene, Pinene, Terpinolene
Route of Administration:  Inhalation
Citation:  Gulluni N, et al. Cannabis Essential Oil: A Preliminary Study for the Evaluation of the Brain Effects. Evid Based Complement Alternat Med. 2018; 2018:1709182. doi: 10.1155/2018/1709182
Authors:  Gulluni N, Re T, Loiacono I, Lanzo G, Gori L, Macchi C, Epifani F, Bragazzi N, Firenzuoli F