PRIMARY STUDY

Monoamine Involvement in the Antidepressant-Like Effect of β-Caryophyllene.

Key Findings:  This study provides a new mechanism of BCP-induced antidepressant-like effect mediated by some sub-types of catecholaminergic neurotransmitter system that could be a candidate for clinical tests of new treatments for depressive disorders.

Type of Study:  Animal Study

Study Result:  Positive

Research Location(s):  Brazil

Year of Pub:  2018


Cannabinoids Studied: 

Phytocannabinoid Source:  Not Applicable

Terpenes Studied:  ß-Caryophyllene

Ligands Studied:  Epinephrine




Citation:  de Oliveira DR, et al. Monoamine Involvement in the Antidepressant-Like Effect of β-Caryophyllene. CNS Neurol Disord Drug Targets. 2018; 17:309-320. doi: 10.2174/1871527317666180420150249

Authors:  de Oliveira DR, da Silva DM, Florentino IF, de Brito AF, Fajemiroye JO, da Silva DPB, da Rocha FF, Costa EA, Galdino PM