Key Findings:  MPP+ (1-methyl-4-phenylpyridinium) has been reported to be a major neurotoxin causing neurotoxic insults on dopaminergic neurons in humans. The authors conclude that BCP might act as a promising therapeutic agent against MPP+ toxicity in neuronal cells.
Type of Study:  Laboratory Study
Study Result:  Positive
Research Location(s):  China
Year of Pub:  2018
Cannabinoids Studied:  Capsaicin (CAPS)
Phytocannabinoid Source:  Not Applicable
Terpenes Studied:  ß-Caryophyllene
Receptors Studied:  CB2
Route of Administration:  In vitro
Citation:  Wang G, et al. β-Caryophyllene (BCP) ameliorates MPP+ induced cytotoxicity. Biomed Pharmacother. 2018; 103:1086-1091. doi: 10.1016/j.biopha.2018.03.168
Authors:  Wang G, Ma W, Du J