In Vitro Model of Neuroinflammation: Efficacy of Cannabigerol, a Non-Psychoactive Cannabinoid

Key Findings:  CBG pre-treatment inhibited apoptosis. Furthermore, CBG pre-treatment counteracted not only inflammation, as demonstrated by the reduction of pro-inflammatory cytokines (i.e. IL-1β, TNF-α, IFN-γ). All together, results demonstrate the neuroprotective effects of CBG, that may be a potential treatment against neuroinflammation and oxidative stress. The results indicated that CBG exerted a protective action in an in vitro neuroinflammation model.

Type of Study:  Laboratory Study

Study Result:  Positive

Cannabinoids Studied:  Cannabigerol (CBG)

Phytocannabinoid Source:  Isolate and Cannabis Extract/Flower

Form of Administration:  Not Applicable

Study Location(s):  Italy

Year of Pub:  2018

Link to study