Key Findings:  CBG pre-treatment inhibited apoptosis. Furthermore, CBG pre-treatment counteracted not only inflammation, as demonstrated by the reduction of pro-inflammatory cytokines (i.e. IL-1β, TNF-α, IFN-γ). All together, results demonstrate the neuroprotective effects of CBG, that may be a potential treatment against neuroinflammation and oxidative stress. The results indicated that CBG exerted a protective action in an in vitro neuroinflammation model.
Type of Study:  Laboratory Study
Study Result:  Positive
Research Location(s):  Italy
Year of Pub:  2018
Cannabinoids Studied:  Cannabigerol (CBG)
Phytocannabinoid Source:  Isolate
Route of Administration:  In vitro
Citation:  Gugliandolo A, et al. In Vitro Model of Neuroinflammation: Efficacy of Cannabigerol, a Non-Psychoactive Cannabinoid. Int J Mol Sci. 2018; 19:(unknown pages). doi: 10.3390/ijms19071992
Authors:  Gugliandolo A, Pollastro F, Grassi G, Bramanti P, Mazzon E