PRIMARY STUDY
β-Caryophyllene ameliorates the Alzheimer-like phenotype in APP/PS1 Mice through CB2 receptor activation and the PPARγ pathway.
Key Findings: Agonists of both CB2 and PPARγ receptors improve AD.
Type of Study: Animal Study
Study Result: Positive
Research Location(s): China
Year of Pub: 2014
Cannabinoids Studied: AM-x Synthetic Cannabinoids
Phytocannabinoid Source: Not Applicable
Terpenes Studied: ß-Caryophyllene
Receptors Studied: CB2, PPAR - Gamma
Route of Administration: Oral (Ingestion)
Citation: Cheng Y, et al. β-Caryophyllene ameliorates the Alzheimer-like phenotype in APP/PS1 Mice through CB2 receptor activation and the PPARγ pathway. Pharmacology. 2014; 94:1-12. doi: 10.1159/000362689
Authors: Cheng Y, Dong Z, Liu S
