Key Findings:  Pharmacological modulation of the eCB system ( Figure 3) has been shown to reduce chronic activation of the neuroinflammatory response, aid in Ca2+ homeostasis, reduce oxidative stress, mitochondrial dysfunction and the resulting proapoptotic cascade, while promoting neurotrophic support.
Type of Study:  Meta-analysis
Study Result:  Positive
Study Location(s):  Ireland
Year of Pub:  2014
Cannabinoids Studied:  Cannabidiol (CBD), Tetrahydrocannabinol (THC), SR-x Synthetic Cannabinoids, Anandamide (AEA), 2-Arachidonoyl Glycerol (2-AG)
Phytocannabinoid Source:  Not Applicable
Receptors Studied:  CB1, CB2
Ligands Studied:  Glutamate