PRIMARY STUDY

Beta-caryophyllene Protects Against Alcoholic Steatohepatitis By Attenuating Inflammation And Metabolic Dysregulation In Mice

Key Findings:  Given the safety of BCP in humans this food additive has a high translational potential in treating or preventing hepatic injury associated with oxidative stress, inflammation and steatosis.

Type of Study:  Animal Study

Study Result:  Positive

Research Location(s):  Switzerland, United States

Year of Pub:  2017


Cannabinoids Studied: 

Phytocannabinoid Source:  Not Applicable

Terpenes Studied:  ß-Caryophyllene

Receptors Studied:  CB2, PPAR - Alpha




Citation:  Varga ZV, et al. β-Caryophyllene protects against alcoholic steatohepatitis by attenuating inflammation and metabolic dysregulation in mice. Br J Pharmacol. 2018; 175:320-334. doi: 10.1111/bph.13722

Authors:  Varga ZV, Matyas C, Erdelyi K, Cinar R, Nieri D, Chicca A, Nemeth BT, Paloczi J, Lajtos T, Corey L, Hasko G, Gao B, Kunos G, Gertsch J, Pacher P