PRIMARY STUDY

The protective effects of β-caryophyllene on LPS-induced primary microglia M1/M2 imbalance: A mechanistic evaluation.

Key Findings:  In conclusion, the low concentration of BCP has higher selective anti-inflammatory effects rather than high levels. On this occasion, BCP by modulating the microglia is able to have potential therapeutic effects in neuro-inflammation conditions and microglia cells such as MS and AD.

Type of Study:  Laboratory Study

Study Result:  Positive

Study Location(s):  Iran

Year of Pub:  2018


Cannabinoids Studied: 

Phytocannabinoid Source:  Not Applicable

Terpenes Studied:  ß-Caryophyllene

Receptors Studied:  CB2, PPAR - Gamma

Ligands Studied:  Anti-inflammatory cytokines, Pro-inflammatory cytokines

Route of Administration:  In vitro



Link to study