PRIMARY STUDY

Cannabidiol Attenuates Cisplatin-Induced Nephrotoxicity by Decreasing Oxidative/Nitrosative Stress, Inflammation, and Cell Death.

Key Findings:  Treatment of mice with cannabidiol markedly attenuated the cisplatin-induced oxidative/nitrosative stress, inflammation, and cell death in the kidney, and it improved renal function. Thus, the results suggest that cannabidiol may represent a promising new protective strategy against cisplatin-induced nephrotoxicity.