PRIMARY STUDY
β-Caryophyllene attenuates palmitate-induced lipid accumulation through AMPK signaling by activating CB2 receptor in human HepG2 hepatocytes.
Key Findings: The results suggest that β-caryophyllene has the potential efficacy in preventing and ameliorating nonalcoholic fatty liver disease and its associated metabolic disorders.
Type of Study: Laboratory Study
Study Result: Positive
Research Location(s): Japan
Year of Pub: 2016
Cannabinoids Studied:
Phytocannabinoid Source: Not Applicable
Terpenes Studied: ß-Caryophyllene
Receptors Studied: CB2
Route of Administration: In vitro
Citation: Kamikubo R, et al. β-Caryophyllene attenuates palmitate-induced lipid accumulation through AMPK signaling by activating CB2 receptor in human HepG2 hepatocytes. Mol Nutr Food Res. 2016; 60:2228-2242. doi: 10.1002/mnfr.201600197
Authors: Kamikubo R, Kai K, Tsuji-Naito K, Akagawa M
