PRIMARY STUDY
The effect of tetrahydrocannabinol:cannabidiol oromucosal spray on cognition: a systematic review
Key Findings: This review of the existing studies on the effects of 1:1 tetrahydrocannabinol (THC) and cannabidiol (CBD) oromucosal spray and whether the CBD can attenuate the psychoactive effects and cognitive abilities. The analysis finds inconsistent results, and there was little difference between the cannabis and the control groups on cognitive function.
Type of Study: Meta-analysis
Study Sample Size: 10
Study Result: Inconclusive
Research Location(s): Canada, Iran
Year of Pub: 2023
Cannabinoids Studied: Cannabidiol (CBD), Tetrahydrocannabinol (THC), Pharma THC:CBD
Phytocannabinoid Source: Unspecified
Chemotype: Chemotype II
Sub-Ratio: THC:CBD (1:1)
Route of Administration: Sublingual/Oromucosal
Citation: Motaghi E, et al. The effect of tetrahydrocannabinol:cannabidiol oromucosal spray on cognition: a systematic review. Eur J Clin Pharmacol. 2023; 79:371-381. doi: 10.1007/s00228-023-03454-y
Authors: Motaghi E, Ghasemi-Pirbaluti M, Rashidi M, Alasvand M, Di Ciano P, Bozorgi H
