PRIMARY STUDY

Urinary, Plasma, and Serum Biomarkers' Utility for Predicting Acute Kidney Injury Associated With Cardiac Surgery in Adults: A Meta-analysis

Key Findings:  This systematic review looked at multiple biomarkers, including neutrophil gelatinase-associated lipocalin (NGAL), cystatin C, IL-18, liver-type fatty acid binding protein (L-FABP), and kidney injury marker 1 (KIM-1) and found they possess modest discrimination to predict kidney injury in cardiac surgery patients.

Type of Study:  Meta-analysis

Study Sample Size:  28

Study Result:  Positive

Research Location(s):  Canada

Year of Pub:  2015


Cannabinoids Studied:  Fatty Acid-Binding Protein (FABP)

Phytocannabinoid Source:  Not Applicable




Citation:  Ho J, Tangri N, Komenda P, Kaushal A, Sood M, Brar R, Gill K, Walker S, MacDonald K, Hiebert BM, Arora RC, Rigatto C. Urinary, Plasma, and Serum Biomarkers' Utility for Predicting Acute Kidney Injury Associated With Cardiac Surgery in Adults: A Meta-analysis. Am J Kidney Dis. 2015 Dec;66(6):993-1005. doi: 10.1053/j.ajkd.2015.06.018. Epub 2015 Aug 5. PMID: 26253993.