PRIMARY STUDY
10.1186/s13098-024-01283-2
Key Findings: This review of animal models of various types of kidney disease finds that targeting cannabinoid receptors, particularly CB1 antagonists and CB2 agonists, can improve kidney function and reduce inflammatory responses, provide renal protective effects, and maintain therapeutic potential.
Type of Study: Meta-analysis
Study Result: Positive
Research Location(s): China
Year of Pub: 2024
Cannabinoids Studied: Endocannabinoid (unspecified)
Phytocannabinoid Source: Not Applicable
Receptors Studied: CB1, CB2, CB1 agonist, CB1 antagonist, CB2 agonist, CB2 antagonist
Ligands Studied: Pro-inflammatory cytokines
Citation: Zhao Z, et al. The intervention of cannabinoid receptor in chronic and acute kidney disease animal models: a systematic review and meta-analysis. Diabetol Metab Syndr. 2024; 16:45. doi: 10.1186/s13098-024-01283-2
Authors: Zhao Z, Yan Q, Xie J, Liu Z, Liu F, Liu Y, Zhou S, Pan S, Liu D, Duan J, Liu Z
