PRIMARY STUDY

Comparative accuracy of biomarkers for the prediction of hospital-acquired acute kidney injury: a systematic review and meta-analysis

Key Findings:  This meta-analysis looking for biomarkers of acute kidney injury finds that neutrophil gelatinase-associated lipocalin (NGAL) had the best predictive accuracy. Other biomarkers assessed were kidney injury molecule-1, liver-type fatty acid-binding protein, interleukin-18, and tissue inhibitor of metalloproteinases-2 × insulin-like growth factor-binding protein-7.

Type of Study:  Meta-analysis

Study Sample Size:  38725

Study Result:  Inconclusive

Research Location(s):  Taiwan

Year of Pub:  2022


Cannabinoids Studied:  Fatty Acid-Binding Protein (FABP)

Phytocannabinoid Source:  Not Applicable

Ligands Studied:  Insulin

Route of Administration:  Endogenous




Citation:  Pan HC, et al. Comparative accuracy of biomarkers for the prediction of hospital-acquired acute kidney injury: a systematic review and meta-analysis. Crit Care. 2022; 26:349. doi: 10.1186/s13054-022-04223-6

Authors:  Pan HC, Yang SY, Chiou TT, Shiao CC, Wu CH, Huang CT, Wang TJ, Chen JY, Liao HW, Chen SY, Huang TM, Yang YF, Lin HY, Chan MJ, Sun CY, Chen YT, Chen YC, Wu VC