PRIMARY STUDY

The efficacy of an association of palmitoylethanolamide and alpha-lipoic acid in patients with chronic prostatitis/chronic pelvic pain syndrome: A randomized clinical trial

Key Findings:  In subjects with chronic prostatitis/chronic pelvic pain treatment with Palmitoylethanolamide plus Alpha-lipoic acid significantly reduced NIH-CPSI score.

Type of Study:  Clinical Trial

Study Sample Size:  44

Study Result:  Positive

Research Location(s):  Italy

Year of Pub:  2017


Cannabinoids Studied:  Palmitoylethanolamide (PEA)

Phytocannabinoid Source:  Unspecified

DOSING DETAILS   

Study Dosing Objective:  Effective Dose, Safety Profile

Established Protocol:  Effective dose

Route of Administration:  Oral (Ingestion)

Dosing Regimen:  Palmitoylethanolamide (300 mg) Alpha-lipoic acid (300 mg)

Treatment Duration:  12 weeks

Clinical Relevance:  Palmitoylethanolamide (PEA) and Alpha-lipoic acid (ALA) shows promising efficacy over Serenoa Repens in patients with CP/CPPS.




Citation:  Giammusso B, et al. The efficacy of an association of palmitoylethanolamide and alpha-lipoic acid in patients with chronic prostatitis/chronic pelvic pain syndrome: A randomized clinical trial. Arch Ital Urol Androl. 2017; 89:17-21. doi: 10.4081/aiua.2017.1.17

Authors:  Giammusso B, Di Mauro R, Bernardini R