PRIMARY STUDY
Antiproliferative effects of essential oils and their major constituents in human renal adenocarcinoma and amelanotic melanoma cells.
Key Findings: This study provided evidence on how cytotoxic activity of the oils is not always related to their major constituents. Beta-caryophyllene and linalool exhibited comparable IC(50) values to the commercial drug vinblastine on the ACHN cell line.
Type of Study: Laboratory Study
Study Result: Positive
Research Location(s): Italy, Lebanon
Year of Pub: 2008
Cannabinoids Studied:
Phytocannabinoid Source: Not Applicable
Terpenes Studied: ß-Caryophyllene, Linalool
Route of Administration: In vitro
Citation: Loizzo MR, et al. Antiproliferative effects of essential oils and their major constituents in human renal adenocarcinoma and amelanotic melanoma cells. Cell Prolif. 2008; 41:1002-1012. doi: 10.1111/j.1365-2184.2008.00561.x
Authors: Loizzo MR, Tundis R, Menichini F, Saab AM, Statti GA, Menichini F
