PRIMARY STUDY
Systemic Changes in Endocannabinoids and Endocannabinoid-like Molecules in Response to Partial Nephrectomy-Induced Ischemia in Humans
Key Findings: Based on body mass, non-obese patients undergoing partial nephrectomy had significantly higher levels of anandamide (AEA) N-oleoylethanolamine (OEA), and N-palmitoylethanolamine (PEA). This information could help develop novel therapeutic options that target the endocannabinoid system in preventing renal ischemia.
Type of Study: Clinical Trial
Study Sample Size: 16
Study Result: Positive
Research Location(s): Israel
Year of Pub: 2023
Cannabinoids Studied: Anandamide (AEA), Endocannabinoid (unspecified), Other Related Compounds, Palmitoylethanolamide (PEA)
Phytocannabinoid Source: Not Applicable
Route of Administration: Endogenous
Citation: Rothner A, et al. Systemic Changes in Endocannabinoids and Endocannabinoid-like Molecules in Response to Partial Nephrectomy-Induced Ischemia in Humans. Int J Mol Sci. 2023; 24:(unknown pages). doi: 10.3390/ijms24044216
Authors: Rothner A, Gov T, Hinden L, Nemirovski A, Tam J, Rosenzweig B
