PRIMARY STUDY

CB2 cannabinoid receptor agonist selectively inhibits the mechanosensitivity of mucosal afferents in the guinea pig bladder

Key Findings:  This study outlines the CB1 and CB2 receptor mechanism in guinea pig bladder mucosal cells, and concludes that the anti-pain and anti-inflammatory properties of CB1 and CB2 receptor inhibition could be a viable target for the treatment of bladder related disorders like cystitis.

Type of Study:  Laboratory Study

Study Result:  Positive

Study Location(s):  Australia

Year of Pub:  2021


Cannabinoids Studied:  Anandamide (AEA), Endocannabinoid (unspecified)

Phytocannabinoid Source:  Not Applicable

Receptors Studied:  CB1, CB2, TRPV1, GPCR