PRIMARY STUDY
Inhibitory effect of standardized cannabis sativa extract and its ingredient cannabidiol on rat and human bladder contractility
Key Findings: Resulting data suggests that plant derived CBD reduces cholinergic-mediated contractility and that this effect is modulated by TRPV-1 in rats but not in humans.
Type of Study: Laboratory Study
Study Result: Inconclusive
Research Location(s): Italy
Year of Pub: 2011
Cannabinoids Studied: Cannabidiol (CBD)
Phytocannabinoid Source: Cannabis Flower derived
Chemotype: Chemotype III
Receptors Studied: TRPV1
Route of Administration: In vitro
Citation: Capasso R, et al. Inhibitory effect of standardized cannabis sativa extract and its ingredient cannabidiol on rat and human bladder contractility. Urology. 2011; 77:1006.e9-1006.e15. doi: 10.1016/j.urology.2010.12.006
Authors: Capasso R, Aviello G, Borrelli F, Romano B, Ferro M, Castaldo L, Montanaro V, Altieri V, Izzo AA
